1. Medical records and initial situation
At the beginning, diagnosis, histology, imaging, previous treatments, current medication, blood results and general condition are reviewed together. The aim is to create a structured basis for an individual assessment.
2. Additional diagnostics
Depending on the clinical question, immune-status testing, follow-up parameters or additional laboratory tests may be useful. Such findings do not replace imaging or established oncological diagnostics.
3. Blood collection and logistics
If manufacturing is planned, blood collection, collection tubes, transport route and timing are coordinated with the practice or clinic and the manufacturing partner.
4. Patient-specific manufacturing
Suitable starting cells are processed under controlled laboratory conditions and developed into dendritic cells. Details of the manufacturing method and product release are the responsibility of the manufacturing partner.
5. Application
After release, the intended cell preparations are administered according to the specifications of the manufacturing partner and the treating practitioner. Number, intervals and route of administration may vary depending on the procedure and medical assessment.
6. Follow-up
Clinical course, imaging, laboratory values and, where appropriate, supplementary follow-up markers should be interpreted together. A single laboratory value cannot reliably demonstrate treatment success.